If you’re struggling with weight loss and exploring GLP-1 medications, you’re not alone. At Pill4Me Pharmacy in Chilliwack, we’re committed to helping you navigate the latest, most effective weight management solutions—including Zepbound and Wegovy.
What Are Zepbound and Wegovy?
Zepbound (tirzepatide) and Wegovy (semaglutide) are two of the most talked-about weight loss medications in Canada and worldwide. Both belong to the GLP-1 receptor agonist class, mimicking hormones that regulate appetite and fullness.
But a recent head-to-head clinical trial, published in the New England Journal of Medicine, revealed a game-changer:
Zepbound led to significantly more weight loss than Wegovy (NEJM, May 2025).
Clinical Results: Zepbound Outperforms Wegovy
In a 72-week comparative study:
- Zepbound users lost an average of 50 pounds (22.8 kg)
- Wegovy users lost around 33 pounds (15 kg)
- Zepbound reduced waist circumference by 7 inches vs. 5 inches with Wegovy
- 32% of Zepbound users lost 25% or more of their body weight, versus 16% for Wegovy
These results suggest that Zepbound is currently the most effective weight loss drug for patients without diabetes but with other weight-related health concerns.
How Do These Medications Work?
- Zepbound (tirzepatide) targets two hormones: GLP-1 and GIP
- Wegovy (semaglutide) targets only GLP-1
By engaging dual pathways, Zepbound appears to enhance appetite suppression and metabolic regulation more effectively.
Are There Side Effects?
Both medications may cause mild to moderate gastrointestinal issues, including:
- Nausea
- Constipation
- Diarrhea
- Vomiting
Roughly 6% of Zepbound users and 8% of Wegovy users discontinued due to side effects.
Cost & Access in Canada
While Zepbound and Wegovy are not yet fully available in Canada, manufacturers have launched U.S.-based programs reducing monthly costs to around $500 or less. Pill4Me Pharmacy continues to monitor Canadian availability closely.
Why Choose Pill4Me Pharmacy for Weight Loss Support?
At Pill4Me Pharmacy in Chilliwack, we help patients manage their weight with:
- GLP-1 medication support
- Personalized medication reviews
- Virtual care and lifestyle guidance
- Free delivery and refill coordination
- Patient-first care model
Next Steps for Your Weight Loss Journey
If you’re considering GLP-1 medications like Zepbound or Wegovy, talk to your doctor, then bring your prescription to Pill4Me Pharmacy. We’ll help you understand the treatment, optimize your plan, and support your health goals every step of the way.